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The world finally has an approved vaccine against Ebola

Enlarge / A man receives a vaccine against Ebola from a nurse outside the Afia Himbi Health Center on July 15, 2019, in Goma. Getty | PAMELA TULIZO

Regulators in Europe have granted the world's first approval of a vaccine against Ebola—and health officials are wasting no time in rolling it out.

The European Commission announced at the start of the week that it had granted a landmark marketing authorization of Merck's Ebola vaccine Ervebo. The vaccine has been in the works since the 2014 West African Ebola outbreak. It is now being used in the ongoing outbreak in the Democratic Republic of Congo based on a "compassionate use" protocol.

The current outbreak in the DRC has killed nearly 2,200 since August 2018, causing nearly 3,300 cases. The outbreak is the second-largest recorded, surpassed only by the 2014 West African outbreak that caused more than 11,000 deaths and 28,000 cases.

Preliminary vaccine data from the current DRC outbreak suggested that Ervebo is 97.5% effective at preventing the devastating viral disease. It protected well over 90,000 people in the outbreak.

The vaccine protects against one of four species of Ebola known to infect humans—the Zaire ebolavirus species. Zaire is responsible for the current outbreak in the DRC, as well as the 2014 West African outbreak, and nearly all other outbreaks recorded since Ebola was first discovered in 1976.

"Finding a vaccine as soon as possible against this terrible virus has been a priority for the international community ever since Ebola hit West Africa five years ago," European Commissioner Vytenis Andriukaitis said in a statement Sunday, November 10. "Today's decision is therefore a major step forward in saving lives in Africa and beyond."

The vaccine was initially developed by researchers at the Public Health Agency of Canada's National Microbiology Laboratory, which subsequently licensed it to NewLink Genetics Corporation. Merck obtained the license in 2014 amid the West African outbreak and developed it further.

The company celebrated the vaccine's approval Monday.

"It is a historic milestone and a testament to the power of science, innovation and public-private partnership," Merck CEO Kenneth Frazier said in a statement. "After recognizing the need and urgency for an Ebola Zaire vaccine, many came together across sectors to answer the global call for outbreak preparedness. We at MerRead More – Source

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